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Multiple Choice

Which of the following is a benzodiazepine used in initial seizure treatment?

In acute seizure management, benzodiazepines are used to rapidly terminate ongoing seizures by enhancing GABA-A receptor activity, which increases inhibitory neurotransmission in the brain. Among these, lorazepam is preferred for initial treatment when given intravenously because it acts quickly and tends to have a longer duration of action in the central nervous system than some alternatives, providing reliable seizure control and reducing early recurrence while preparing other anticonvulsants if needed. The other options listed are anticonvulsants but not benzodiazepines: levetiracetam is commonly used as an adjunct or for maintenance, valproic acid is broad-spectrum but not a benzodiazepine, and fosphenytoin is a hydantoin used as a second-line agent after benzodiazepines.

In acute seizure management, benzodiazepines are used to rapidly terminate ongoing seizures by enhancing GABA-A receptor activity, which increases inhibitory neurotransmission in the brain. Among these, lorazepam is preferred for initial treatment when given intravenously because it acts quickly and tends to have a longer duration of action in the central nervous system than some alternatives, providing reliable seizure control and reducing early recurrence while preparing other anticonvulsants if needed. The other options listed are anticonvulsants but not benzodiazepines: levetiracetam is commonly used as an adjunct or for maintenance, valproic acid is broad-spectrum but not a benzodiazepine, and fosphenytoin is a hydantoin used as a second-line agent after benzodiazepines.