Which of the following is used as abortive therapy for migraines?

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Multiple Choice

Which of the following is used as abortive therapy for migraines?

Abortive therapy is about stopping a migraine once it starts. NSAIDs fit this role because they block cyclooxygenase enzymes, reducing prostaglandin production. That lowers inflammation and diminishes the sensitization of the trigeminovascular system that drives migraine pain, helping to relieve the attack when taken at the onset. They’re commonly effective for mild to moderate migraines and are a preferred first-line option for acute treatment. Opioids, while sometimes used for severe pain, carry risks of dependence and medication-overuse headaches, so they aren’t ideal for routine abortive therapy. Amitriptyline is a preventive medication, not an acute treatment, so it doesn’t address an ongoing attack. Botox is used for chronic migraine prevention, not as immediate relief for a single episode.

Abortive therapy is about stopping a migraine once it starts. NSAIDs fit this role because they block cyclooxygenase enzymes, reducing prostaglandin production. That lowers inflammation and diminishes the sensitization of the trigeminovascular system that drives migraine pain, helping to relieve the attack when taken at the onset. They’re commonly effective for mild to moderate migraines and are a preferred first-line option for acute treatment.

Opioids, while sometimes used for severe pain, carry risks of dependence and medication-overuse headaches, so they aren’t ideal for routine abortive therapy. Amitriptyline is a preventive medication, not an acute treatment, so it doesn’t address an ongoing attack. Botox is used for chronic migraine prevention, not as immediate relief for a single episode.

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