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Multiple Choice

What best describes Todd's paralysis after a seizure?

Todd’s paralysis is a temporary postictal focal neurologic deficit that follows a seizure. It most often presents as unilateral weakness or paralysis in the aftermath of a seizure and can involve the entire side or just a part of the body. The key feature is that it is transient and typically resolves completely, with average durations around 15 hours, though it can last longer in some cases. The underlying idea is temporary neuronal exhaustion or inhibition in the brain area that generated the seizure, leading to reversible impairment of motor pathways rather than permanent damage. This phenomenon can resemble a stroke, which is why recognizing the seizure context is important: there is a recent seizure and a lack of lasting deficits after the episode. Imaging and EEG usually don’t show an acute lesion corresponding to a stroke; instead, EEG may show postictal slowing in the affected region. It is not a sensory aura and it is not a type of generalized seizure, and the deficit is not permanent, which is why the described postictal, transient unilateral weakness best fits Todd’s paralysis.

Todd’s paralysis is a temporary postictal focal neurologic deficit that follows a seizure. It most often presents as unilateral weakness or paralysis in the aftermath of a seizure and can involve the entire side or just a part of the body. The key feature is that it is transient and typically resolves completely, with average durations around 15 hours, though it can last longer in some cases. The underlying idea is temporary neuronal exhaustion or inhibition in the brain area that generated the seizure, leading to reversible impairment of motor pathways rather than permanent damage.

This phenomenon can resemble a stroke, which is why recognizing the seizure context is important: there is a recent seizure and a lack of lasting deficits after the episode. Imaging and EEG usually don’t show an acute lesion corresponding to a stroke; instead, EEG may show postictal slowing in the affected region. It is not a sensory aura and it is not a type of generalized seizure, and the deficit is not permanent, which is why the described postictal, transient unilateral weakness best fits Todd’s paralysis.